Chlamydial lipopolysaccharide

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O-5: The In vivo Effect of Chlamydial and Total Lipopolysaccharide on Semen Quality

Background: Lipopolysaccharide (LPS) is a major component of Chlamydia spp, and of all Gram-negative bacteria. The role of LPS in alteration of sperm parameters is controversial. In this study quantification of Chlamydia-specific and general lipopolysaccharide in semen was correlated to semen quality. Materials and Methods: 255 male partners of infertile couples were recruited to produce urine ...

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Chlamydial virulence determinants in atherogenesis: the role of chlamydial lipopolysaccharide and heat shock protein 60 in macrophage-lipoprotein interactions.

Data from a spectrum of epidemiologic, pathologic, and animal model studies show that Chlamydia pneumoniae infection is associated with coronary artery disease, but it is not clear how the organism may initiate or promote atherosclerosis. It is postulated that C. pneumoniae triggers key atherogenic events through specific virulence determinants. C. pneumoniae induces mononuclear phagocyte foam ...

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A Chlamydia pneumoniae component that induces macrophage foam cell formation is chlamydial lipopolysaccharide.

Chlamydia pneumoniae infection is associated with atherosclerotic heart and vessel disease, but a causal relationship between this pathogen and the disease process has not been established. Recently, it was reported that C. pneumoniae induces human macrophage foam cell formation, a key event in early atheroma development, suggesting a role for the organism in atherogenesis. This study further e...

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Accumulation of chlamydial lipopolysaccharide antigen in the plasma membranes of infected cells.

The presence of a chlamydia-specified antigen associated with the plasma membrane of infected cell lines was demonstrated by indirect immunofluorescence staining with a monoclonal antibody, designated 47A2, specific for the chlamydial genus-specific lipopolysaccharide (LPS) antigen. Staining of HeLa, L-929, and McCoy cells infected with the L2 or F serovar of Chlamydia trachomatis was observed ...

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Characterization of murine monoclonal and murine, rabbit, and human polyclonal antibodies against chlamydial lipopolysaccharide.

Murine monoclonal and rabbit, murine, and human polyclonal antibodies against chlamydial lipopolysaccharide (LPS) were characterized by the passive hemolysis and passive hemolysis inhibition assays and by absorption experiments with LPSs of Chlamydia psittaci, Chlamydia trachomatis, and a recombinant strain of Salmonella minnesota Re (r595-207) expressing the chlamydia-specific LPS epitope, as ...

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ژورنال

عنوان ژورنال: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

سال: 1999

ISSN: 0925-4439

DOI: 10.1016/s0925-4439(99)00061-7